Listen to a Podcast About Longevity Science

Explore the biology of aging and the cutting-edge research on extending healthy lifespan — telomeres, senescent cells, caloric restriction, rapamycin, and the quest to slow or reverse aging.

Elizabeth Blackburn, Carol Greider, and Jack Szostak won the 2009 Nobel Prize for discovering how telomeres and the enzyme telomerase protect chromosomes — research that revealed a molecular clock of aging in every cell. Caloric restriction studies in rhesus monkeys at the University of Wisconsin, published in 2009 and 2014, showed that eating 30% fewer calories extended lifespan and dramatically reduced age-related diseases. The drug rapamycin, originally discovered in Easter Island soil bacteria in 1972, has extended lifespan by up to 25% in mice, making it one of the most promising pharmacological candidates for human aging intervention.

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