Listen to a Podcast About Aging and Geriatrics

Explore the biology of aging and the medicine of older adults — telomeres, senescent cells, age-related diseases, and the interventions aiming to extend healthspan, not just lifespan.

The "Blue Zones" — five regions identified by Dan Buettner where people live disproportionately long lives (Okinawa, Sardinia, Nicoya, Ikaria, and Loma Linda) — share common lifestyle factors including plant-based diets, daily natural movement, strong social connections, and sense of purpose. Senolytic drugs, which selectively destroy senescent "zombie" cells that accumulate with age and drive inflammation, showed in a 2018 Mayo Clinic study that clearing these cells in mice extended healthy lifespan by 36%. By 2050, the global population aged 65 and older is projected to reach 1.6 billion (16% of the world's population), up from 761 million in 2021, creating unprecedented demands on healthcare systems and eldercare infrastructure.

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